Article
Relevance of single-nucleotide polymorphisms in human TLR genes to infectious and inflammatory diseases and cancer.
Genes and immunity - 1 Apr 2014
Trejo-de la O A, Hernández-Sancén P, Maldonado-Bernal C
Abstract excerpt
Innate and adaptive immune responses in humans have evolved as protective mechanisms against infectious microorganisms. Toll-like receptors (TLRs) have an important role in the recognition of invading microorganisms. TLRs are the first receptors to detect potential pathogens and to initiate the immune response, and they form the crucial link between the innate and adaptive immune responses. TLRs also have an...
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