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Article

Association between the g.14461A>G genetic polymorphism of the TLR4 gene and type 2 diabetes mellitus risk in a Chinese population.

Genetic testing and molecular biomarkers - 1 Apr 2014

Lei Tao, Tang Wenjun, Xiong Yanqin, Zhai Yujuan, Sun Xianghua, Zhang Keqin

Abstract excerpt

OBJECTIVE: Toll-like receptor 4 (TLR4) is an important candidate gene for mediating the susceptibility to type 2 diabetes mellitus (T2DM). The purpose of this study was to investigate the association between the TLR4 gene polymorphisms and T2DM susceptibility. METHODS: A total of 671 T2DM patients and 677 healthy controls were recruited in this study. The created restriction site-polymerase chain reaction and DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24444085
DOI: 10.1089/gtmb.2013.0441

Genes

TLR4

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