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Article

Family association study between tumour necrosis factor a gene polymorphisms and polycystic ovary syndrome in Han Chinese.

Reproductive biomedicine online - 1 Nov 2014

Diao Xinghua, Han Ting, Zhang Yingchun, Ma Jinlong, Shi Yuhua, Chen Zi-Jiang

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a complex disease involving genetic and environmental components. Tumour necrosis factor a (TNFa) is a proinflammatory cytokine in the pathogenesis of PCOS. The genetic association between polymorphisms of TNFa gene and PCOS was investigated. A family based study was conducted with 216 family trios (648 participants) having a proband with PCOS. Transmission disequilibrium test...

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Identifiers

PMID: 25246119
DOI: 10.1016/j.rbmo.2014.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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