Article
The promoter -1031(T/C) polymorphism in tumor necrosis factor-alpha associated with polycystic ovary syndrome.
Reproductive biology and endocrinology : RB&E - 4 Oct 2011
Yun Ji-Hyun, Choi Jin-Woo, Lee Kyung-Ju, Shin Joong-Sik, Baek Kwang-Hyun
Abstract excerpt
BACKGROUND: A tumor necrosis factor-alpha is a multifunctional pro-inflammation cytokine, which has been considered as one of pathogenic factors for various diseases. The promoter -1031(T/C) polymorphism in the tumor necrosis factor-alpha gene was reported that it plays a part in reproduction-related diseases. Among these, polycystic ovary syndrome (PCOS) is known to be a common gynecological disease of women in...
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