Article
Family-based analysis of eight susceptibility loci in polycystic ovary syndrome.
Scientific reports - 29 Jul 2015
Zhao Shigang, Tian Ye, Gao Xuan, Zhang Xiuqing, Liu Hongbin, You Li, Cao Yongzhi, Su Shizhen, Chan Wai-Yee, Sun Yun, Zhao Han, Chen Zi-Jiang
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that is proposed to have a genetic basis. A recent genome-wide association study (GWAS) identified eight new risk loci that are independently associated with PCOS. To further validate the findings, a total of 321 case-parent trios (963 participants) who had a proband affected with PCOS were recruited for the family-based study. The transmission...
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