Article
Family-Based Association Study of rs17300539 and rs12495941 Polymorphism in Adiponectin Gene and Polycystic Ovary Syndrome in a Chinese Population.
Medical science monitor : international medical journal of experimental and clinical research - 6 Jan 2017
Sun Xianchang, Wu Xingguo, Duan Yunmin, Liu Guanghai, Yu Xinyan, Zhang Wenjuan
Abstract excerpt
BACKGROUND Polycystic ovary syndrome (PCOS) is a complex disease that has both genetic and environmental components. Adiponectin plays an important role in the regulation of insulin sensitivity and insulin resistance (IR) in PCOS. The aim of this study was to determine 2 single-nucleotide polymorphisms (SNPs) variants (rs12495941 and rs17300539) of the adiponectin gene (ADIPOQ) in polycystic ovary syndrome (PCOS)...
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