Article
Genetic association of CTLA4 gene with polycystic ovary syndrome in the Chinese Han population.
Medicine - 1 Jul 2018
Su Jing, Li Yan, Su Guanglong, Wang Jing, Qiu Ting, Ma Rong, Zhao Lei
Abstract excerpt
The autoimmune and gene etiology are implicated in the pathogenesis of polycystic ovary syndrome (PCOS). The cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) is important for negative regulation of T-cell activation, and CTLA4 gene has been identified as a risk factor for some autoimmune diseases. However, none studies have been performed about the association between PCOS and the CTLA4 gene before. Here, we...
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