Article
Family-based analysis of GGT1 and HNF1A gene polymorphisms in patients with polycystic ovary syndrome.
Reproductive biomedicine online - 1 Jan 2018
Xu Xinghua, Qin Lang, Tian Ye, Wang Min, Li Guangyao, Du Yanzhi, Chen Zi-Jiang, Li Weiping
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic disease. Previous studies indicate that genes GGT1 and HNF1A may contribute to the abnormal glucose metabolism and altered lipid profile that are important clinical features of PCOS. In the current study, the correlation between polymorphisms in the GGT1 and HNF1A genes and PCOS was explored. A total of 310 family trios were studied and the...
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