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Associations Between Early Life Stress and Gene Methylation in Children

24 Jul 2014

Abstract excerpt

Children exposed to extreme stress are at heightened risk for developing mental and physical disorders. However, little is known about mechanisms underlying these associations in humans. An emerging insight is that children's social environments change gene expression, which contributes to biological vulnerabilities for behavioral problems. Epigenetic changes in the glucocorticoid receptor gene, a critical...

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PMID: 25056599
DOI: 10.1111/cdev.12270

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