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Article

The role of childhood trauma, HPA axis reactivity and FKBP5 genotype on cognition in healthy individuals.

Psychoneuroendocrinology - 1 Jun 2021

Ferrer Alex, Soria Virginia, Salvat-Pujol Neus, Martorell Lourdes, Armario Antonio, Urretavizcaya Mikel, Gutiérrez-Zotes Alfonso, Monreal José Antonio, Crespo José Manuel, Massaneda Clara, Vilella Elisabet, Palao Diego, Menchón José Manuel, Labad Javier

Abstract excerpt

Cognitive impairment has been associated with both childhood adversity and abnormalities of hypothalamic-pituitary-adrenal (HPA) axis function. An interaction exists between the functional polymorphism rs1360780 in the FKBP5 gene and childhood maltreatment, influencing a variety of clinical outcomes. Our goal was to study the relationship between different types of childhood trauma, HPA axis functionality,...

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Identifiers

PMID: 33866068
DOI: 10.1016/j.psyneuen.2021.105221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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