Article
Interaction of the ADRB2 gene polymorphism with childhood trauma in predicting adult symptoms of posttraumatic stress disorder.
JAMA psychiatry - 1 Oct 2014
Liberzon Israel, King Anthony P, Ressler Kerry J, Almli Lynn M, Zhang Peng, Ma Sean T, Cohen Gregory H, Tamburrino Marijo B, Calabrese Joseph R, Galea Sandro
Abstract excerpt
IMPORTANCE: Posttraumatic stress disorder (PTSD), while highly prevalent (7.6% over a lifetime), develops only in a subset of trauma-exposed individuals. Genetic risk factors in interaction with trauma exposure have been implicated in PTSD vulnerability. OBJECTIVE: To examine the association of 3755 candidate gene single-nucleotide polymorphisms with PTSD development in interaction with a history of childhood...
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