Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A.

Development (Cambridge, England) - 1 Oct 2014

Li Wei, Klovstad Martha, Schüpbach Trudi

Abstract excerpt

In Drosophila melanogaster, the anteroposterior (AP) and dorsoventral (DV) axes of the oocyte and future embryo are established through the localization and translational regulation of gurken (grk) mRNA. This process involves binding of specific factors to the RNA during transport and a dynamic remodeling of the grk-containing ribonucleoprotein (RNP) complexes once they have reached their destination within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Egg Proteins
Share to Meiosis
Share to Oocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oogenesis

Share to Polyribosomes

Share to Ribonucleoproteins

Share to Transforming Growth Factor alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 25231760
DOI: 10.1242/dev.109306
PMCID: PMC4197705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A.PMID 25231760Read ↗

Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila.Semantic proximity Read ↗

The RNA-binding protein Squid is required for the establishment of anteroposterior polarity in the Drosophila oocyte.Semantic proximity Read ↗

Squid is required for efficient posterior localization of oskar mRNA during Drosophila oogenesis.Semantic proximity Read ↗

spn-F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila.Semantic proximity Read ↗

Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis.Semantic proximity Read ↗

Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis.Semantic proximity Read ↗

Functioning of the Drosophila orb gene in gurken mRNA localization and translation.Semantic proximity Read ↗

CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint.Semantic proximity Read ↗

Oocyte polarity depends on regulation of gurken by Vasa.Semantic proximity Read ↗

okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis.Semantic proximity Read ↗

Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes.Semantic proximity Read ↗

Activation of a meiotic checkpoint during Drosophila oogenesis regulates the translation of Gurken through Chk2/Mnk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.