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Article

Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes.

Development (Cambridge, England) - 1 Dec 1997

González-Reyes A, Elliott H, St Johnston D

Abstract excerpt

The two main body axes in Drosophila become polarised as a result of a series of symmetry-breaking steps during oogenesis. Two of the sixteen germline cells in each egg chamber develop as pro-oocytes, and the first asymmetry arises when one of these cells is selected to become the oocyte. Anterior-posterior polarity originates when the oocyte then comes to lie posterior to the nurse cells and signals through the...

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Identifiers

PMID: 9362456
DOI: 10.1242/dev.124.24.4927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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