Article
spn-F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila.
Development (Cambridge, England) - 1 Apr 2006
Abdu Uri, Bar Dikla, Schüpbach Trudi
Abstract excerpt
The anteroposterior and dorsoventral axes of the Drosophila embryo are established during oogenesis through the activities of Gurken (Grk), a Tgfalpha-like protein, and the Epidermal growth factor receptor (Egfr). spn-F mutant females produce ventralized eggs similar to the phenotype produced by mutations in the grk-Egfr pathway. We found that the ventralization of the eggshell in spn-F mutants is due to defects...
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