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Article

HIV-1 Env-specific memory and germinal center B cells in C57BL/6 mice.

Viruses - 5 Sept 2014

Soldemo Martina, Pedersen Gabriel K, Karlsson Hedestam Gunilla B

Abstract excerpt

Continued efforts to define the immunogenic properties of the HIV-1 envelope glycoproteins (Env) are needed to elicit effective antibody (Ab) responses by vaccination. HIV-1 is a highly neutralization-resistant virus due to conformational and glycan shielding of conserved Ab determinants on the virus spike. Elicitation of broadly neutralizing Abs that bind poorly accessible epitope regions on Env is therefore...

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Share to Antibodies, Neutralizing
Share to Antibody Formation
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germinal Center

Share to HIV Antibodies

Share to Immunoglobulin G

Share to Immunologic Memory

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Source

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Identifiers

PMID: 25198199
DOI: 10.3390/v6093400
PMCID: PMC4189027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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