Article
Genome-wide detection of allelic gene expression in hepatocellular carcinoma cells using a human exome SNP chip.
Gene - 10 Nov 2014
Park Yon Mi, Cheong Hyun Sub, Lee Jong-Keuk
Abstract excerpt
Allelic variations in gene expression influence many biological responses and cause phenotypic variations in humans. In this study, Illumina Human Exome BeadChips containing more than 240,000 single nucleotide polymorphisms (SNPs) were used to identify changes in allelic gene expression in hepatocellular carcinoma cells following lipopolysaccharide (LPS) stimulation. We found 17 monoallelically expressed genes,...
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