Article
Allelic variation in gene expression is common in the human genome.
Genome research - 1 Aug 2003
Lo H Shuen, Wang Zhining, Hu Ying, Yang Howard H, Gere Sheryl, Buetow Kenneth H, Lee Maxwell P
Abstract excerpt
Variations in gene sequence and expression underlie much of human variability. Despite the known biological roles of differential allelic gene expression resulting from X-chromosome inactivation and genomic imprinting, a large-scale analysis of allelic gene expression in human is lacking. We examined allele-specific gene expression of 1063 transcribed single-nucleotide polymorphisms (SNPs) by using Affymetrix...
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