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Article

Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells.

Nucleic acids research - 1 Jan 2007

Milani Lili, Gupta Manu, Andersen Malin, Dhar Sumeer, Fryknäs Mårten, Isaksson Anders, Larsson Rolf, Syvänen Ann-Christine

Abstract excerpt

Using the relative expression levels of two SNP alleles of a gene in the same sample is an effective approach for identifying cis-acting regulatory SNPs (rSNPs). In the current study, we established a process for systematic screening for cis-acting rSNPs using experimental detection of AI as an initial approach. We selected 160 expressed candidate genes that are involved in cancer and anticancer drug resistance...

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Share to Allelic Imbalance
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Drug Resistance, Neoplasm

Share to Electrophoretic Mobility Shift Assay

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Source

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Identifiers

PMID: 17267408
DOI: 10.1093/nar/gkl1152
PMCID: PMC1865061

Genes

APC
BCL2
CCND2
MLH1
PARP1
SLIT2
XRCC1
YES1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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