Article
Association of IRGM gene mutations with inflammatory bowel disease in the Indian population.
PloS one - 1 Jan 2014
Baskaran Kirankumar, Pugazhendhi Srinivasan, Ramakrishna Balakrishnan S
Abstract excerpt
BACKGROUND: Mutations in the IRGM gene have been associated with Crohn's disease in several populations but have not been explored in Indian patients with this disease. This study examined the association of IRGM mutations with ulcerative colitis and Crohn's disease in Indian patients with inflammatory bowel disease. METHODS: The IRGM gene was amplified in four segments and Sanger-sequenced in 101 participants...
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