Article
Genetic polymorphisms of ATG16L1 and IRGM genes in Malaysian patients with Crohn's disease.
Journal of digestive diseases - 1 Jan 2020
Kee Boon Pin, Ng Jin Guan, Ng Ching Ching, Hilmi Ida, Goh Khean Lee, Chua Kek Heng
Abstract excerpt
OBJECTIVE: To investigate the association between genetic polymorphisms in ATG16L1 and IRGM genes and the development of Crohn's disease (CD) in Malaysian patients. METHODS: Altogether 335 participants were recruited, including 85 patients with CD and 250 unrelated healthy controls, and their informed consent was obtained. Genomic DNA was extracted via a conventional phenol-chloroform extraction method. Six...
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