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Article

Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA.

PloS one - 1 Jan 2014

Hudson William H, Youn Christine, Ortlund Eric A

Abstract excerpt

The steroid hormone receptors regulate important physiological functions such as reproduction, metabolism, immunity, and electrolyte balance. Mutations within steroid receptors result in endocrine disorders and can often drive cancer formation and progression. Despite the conserved three-dimensional structure shared among members of the steroid receptor family and their overlapping DNA binding preference,...

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Share to Crystallography, X-Ray
Share to Protein Structure, Secondary
Share to Pseudohypoaldosteronism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Glucocorticoid

Share to Receptors, Mineralocorticoid

Share to Recombinant Proteins

Share to Sequence Alignment

Share to Structural Homology, Protein

Source

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Identifiers

PMID: 25188500
DOI: 10.1371/journal.pone.0107000
PMCID: PMC4154765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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