Article
The vitamin D hormone and its nuclear receptor: molecular actions and disease states.
The Journal of endocrinology - 1 Sept 1997
Haussler M R, Haussler C A, Jurutka P W, Thompson P D, Hsieh J C, Remus L S, Selznick S H, Whitfield G K
Abstract excerpt
Vitamin D plays a major role in bone mineral homeostasis by promoting the transport of calcium and phosphate to ensure that the blood levels of these ions are sufficient for the normal mineralization of type I collagen matrix in the skeleton. In contrast to classic vitamin D-deficiency rickets, a number of vitamin D-resistant rachitic syndromes are caused by acquired and hereditary defects in the metabolic...
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