Article
Transcription efficiency of different chicken mannose-binding lectin promoter alleles.
Immunogenetics - 1 Dec 2014
Kjærup R M, Dalgaard T S, Norup L R, Goto R M, Miller M M, Sørensen P, Juul-Madsen H R
Abstract excerpt
The serum collectin mannose-binding lectin (MBL) plays a major role in innate immunity by activation of the lectin complement pathway or by acting as an opsonin. The serum levels of human and animal MBL are associated with susceptibility to a wide range of infections, and the variation of MBL in serum is genetically determined. In the chicken, 14 single nucleotide polymorphisms (SNPs) have so far been found in...
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