Article
Single-nucleotide polymorphisms in porcine mannan-binding lectin A.
Immunogenetics - 1 Dec 2006
Lillie Brandon N, Keirstead Natalie D, Squires E James, Hayes M Anthony
Abstract excerpt
The MBL1 and MBL2 genes encode mannan-binding lectins (MBL) A and C, respectively, that are collagenous lectins (collectins) produced mainly by the liver. Several single-nucleotide polymorphisms (SNPs) in the human MBL2 gene are responsible for various innate immune dysfunctions due to abnormal structure or expression of human MBL-C. The MBL1 gene encodes MBL-A, which has bacteria-binding properties in pigs and...
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