Article
Mannose-binding lectin 1 haplotypes influence serum MBL-A concentration, complement activity, and milk production traits in Chinese Holstein cattle.
Immunogenetics - 1 Nov 2011
Liu Jianbo, Ju Zhihua, Li Qiuling, Huang Jinming, Li Rongling, Li Jiangbin, Ma Lijuan, Zhong Jifeng, Wang Changfa
Abstract excerpt
Mannose-binding lectin (MBL) is a member of the collectin protein family that binds a broad range of microorganisms and activates the lectin-complement pathway of innate immunity. MBL deficiency is associated with an increased risk for various infections and arises from five polymorphisms in the promoter and first exon of the MBL gene in humans. In this study, three novel single-nucleotide polymorphisms (SNPs) in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
