Article
Structural gene variants in the porcine mannose-binding lectin 1 (MBL1) gene are associated with low serum MBL-A concentrations.
Immunogenetics - 1 May 2011
Juul-Madsen Helle R, Kjærup Rikke M, Toft Charlotte, Henryon Mark, Heegaard Peter M H, Berg Peer, Dalgaard Tina S
Abstract excerpt
Mannose-binding lectin (MBL) is a collagenous lectin that kills a wide range of pathogenic microbes through complement activation. The MBL1 and MBL2 genes encode MBL-A and MBL-C, respectively. MBL deficiency in humans is associated with higher susceptibility to viral as well as bacterial infections. A number of single nucleotide polymorphisms (SNP) have been identified in the collagen-like domain of the human MBL...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
