Article
Characterization of the NLRC5 promoter in chicken: SNPs, regulatory elements and CpG islands.
Animal genetics - 1 Oct 2016
Guo X M, Liu X P, Chang G B, Xu L, Bi Y L, Wang H Z, Zhang Y, Zhu P F, Wu Y, Chen G H
Abstract excerpt
NLRC5 plays an important role in the innate immunity and cellular immunity in many species, but the regulatory mechanism of NLRC5 expression in chickens remains unclear. In this study, a series of deletion fragments of the NLRC5 promoter region were constructed and dual-luciferase assay was performed. Then, we detected the SNP in the core region and its function. Important transcriptional regulatory elements were...
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