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Article

Chicken mannose-binding lectin (MBL) gene variants with influence on MBL serum concentrations.

Immunogenetics - 1 Jun 2013

Kjærup Rikke M, Norup Liselotte R, Skjødt Karsten, Dalgaard Tina S, Juul-Madsen Helle R

Abstract excerpt

Mannose-binding lectin (MBL) plays a major role in the innate immune defence by activating the lectin complement pathway or by acting as an opsonin. Two forms of MBL have been characterised from several species, but for humans and chickens, only one form of functional MBL has been described. The human MBL2 gene is highly polymorphic, and it causes varying MBL serum levels. Several of the single-nucleotide...

Topics

Alleles
Animals
Base Sequence
Chickens
Mannose-Binding Lectin
Molecular Sequence Data
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
TATA Box

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23455474
DOI: 10.1007/s00251-013-0689-6

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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