Article
Restricted polymorphisms of the mannose-binding lectin gene in a population of Papua New Guinea.
Mutation research - 29 Aug 2002
Jüliger Simone, Kremsner Peter G, Alpers Michael P, Reeder John C, Kun Jürgen F J
Abstract excerpt
The human mannose-binding lectin (MBL) is an important protein of the innate immune system. MBL is able to eliminate potential pathogens by activating the complement cascade or by opsonisation. We investigated the gene and promoter region of MBL in a population from Papua New Guinea infected with Plasmodium falciparum parasites and measured the appropriate serum concentrations of these individuals. Their serum...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
