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Article

Rexinoid inhibits Nrf2-mediated transcription through retinoid X receptor alpha.

Biochemical and biophysical research communications - 26 Sept 2014

Wu Jiaguo, Wang Hongyan, Tang Xiuwen

Abstract excerpt

NF-E2 P45-related factor 2 (Nrf2) is a key transcription factor that controls genes encoding cytoprotective and detoxifying enzymes through antioxidant response elements (AREs) in their regulatory regions. We reported recently that retinoid X receptor alpha (RXRα) inhibits Nrf2 function by direct interaction with the Neh7 domain of Nrf2 in a ligand-independent manner. Here, we provide evidence that an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kelch-Like ECH-Associated Protein 1

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Source

Identifiers

PMID: 25172665
DOI: 10.1016/j.bbrc.2014.08.111

Genes

KEAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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