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Article

Nrf2 as a target for cancer chemoprevention.

Mutation research - 11 Dec 2005

Yu Xiang, Kensler Thomas

Abstract excerpt

Chemical insults, whether of endogenous or exogenous origins, play major roles in the etiopathogenesis of many cancers. As such, strategies to blunt their formation and limit their damage to biomolecules are a central aspect of chemoprevention. Cellular defenses against such insults are regulated in part by the transcription factor Nrf2. Nrf2, in turn, regulates gene expression through interactions with the ARE...

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Identifiers

PMID: 16054659
DOI: 10.1016/j.mrfmmm.2005.04.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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