Article
The pharmacological manipulation of the Nrf2 pathway and its therapeutic significance
2014-01-01
Abstract excerpt
Nrf2 (Nuclear factor erythroid 2-related factor 2), a redox-sensitive transcription factor, plays a critical role in the regulation of cellular defence and contributes to a number of cellular processes. Nrf2 is regulated through an interplay of complex transcriptional and post-translational mechanisms that modulates its activity during cellular perturbations or other biological processes thereby ensuring cellular...
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Identifiers and source
- Literature Corpus work
- 9e59012b-6d9f-5297-8cc9-e4596c7b80b1
- DOI
- 10.17638/02035060