Article
Effects of GWAS-associated genetic variants on lncRNAs within IBD and T1D candidate loci.
PloS one - 1 Jan 2014
Mirza Aashiq H, Kaur Simranjeet, Brorsson Caroline A, Pociot Flemming
Abstract excerpt
Long non-coding RNAs are a new class of non-coding RNAs that are at the crosshairs in many human diseases such as cancers, cardiovascular disorders, inflammatory and autoimmune disease like Inflammatory Bowel Disease (IBD) and Type 1 Diabetes (T1D). Nearly 90% of the phenotype-associated single-nucleotide polymorphisms (SNPs) identified by genome-wide association studies (GWAS) lie outside of the protein coding...
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