Article

eQTL in diseased colon tissue identifies novel target genes associated with IBD

2024-10-17

Abstract excerpt

Genome-wide association studies (GWAS) have identified over 300 loci associated with the inflammatory bowel diseases (IBD), but putative causal genes for most are unknown. We conducted the largest disease-focused expression quantitative trait loci (eQTL) analysis using colon tissue from 252 IBD patients to determine genetic effects on gene expression and potential contribution to IBD. Combined with two non-IBD col...

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Literature Corpus work: f2944fb2-bac1-52a5-9aa7-e67255594c1c
DOI: 10.1101/2024.10.14.618229

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