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Article

Functional Implications of Intergenic GWAS SNPs in Immune-Related LncRNAs.

Advances in experimental medicine and biology - 1 Jan 2022

Castellanos-Rubio Ainara, Ghosh Sankar

Abstract excerpt

Genome wide association studies (GWAS) have identified many loci contributing to genetic variation of complex traits. Immune mediated disorders are complex diseases for which hundreds of risk alleles have been identified by GWAS. However, the intergenic location of most of the signals has make it difficult to decipher their implication in disease pathogenesis. A significant number of immune disease-associated...

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PMID: 35220569
DOI: 10.1007/978-3-030-92034-0_8

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