Article
Mechanisms and functions of lncRNAs linked to autoimmune disease risk alleles.
Advances in immunology - 1 Jan 2024
Tian Ruxiao, Ghosh Sankar
Abstract excerpt
Recent advances in human genomics technologies have helped uncover genetic risk alleles for many complex autoimmune diseases. Intriguingly, over 90% of genome-wide association study (GWAS) risk alleles reside within the non-coding regions of the genome. An emerging new frontier of functional and mechanistic studies have shed light on the functional relevance of risk alleles that lie within long noncoding RNAs...
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