Article

Reference-guided Genome Assembly of Long Non-coding RNA Transcripts Reveals Target Genes Associated With Crohn’s Disease

2025-10-01

Abstract excerpt

Crohn’s disease (CD) is highly heterogeneous in presentation and progression with no cure. Molecular phenotyping has been used to elucidate cellular and tissue-based alterations to characterize drivers and effects of disease. One currently understudied class of functional molecules is long non-coding RNAs (lncRNAs). Studying the full lncRNA landscape in IBD is challenging due in part to an incomplete lncRNA annota...

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Literature Corpus work: 7c539dfa-ef25-5236-a017-772c0bb294d5
DOI: 10.1101/2025.09.30.674088

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