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Article

Understanding the link between regulatory RNA regions and genomic variation in coeliac disease.

Advances in genetics - 1 Jan 2025

Pascual-González Izei, Santin Izortze, Castellanos-Rubio Ainara

Abstract excerpt

Coeliac disease (CD) is a chronic immune-mediated inflammatory disorder triggered by dietary gluten ingestion in genetically predisposed individuals. While gluten-specific T cells and HLA-DQ2/DQ8 alleles are critical to the disease onset, they account for less than half of the genetic heritability, underscoring the complexity of CD's genetic underpinnings. Genome-Wide Association Studies (GWAS) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40818857
DOI: 10.1016/bs.adgen.2025.02.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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