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Article

CHRNA9 polymorphisms and smoking exposure synergize to increase the risk of breast cancer in Taiwan.

Carcinogenesis - 1 Nov 2014

Hsieh Yi-Chen, Lee Chia-Hwa, Tu Shih-Hsin, Wu Chih-Hsiung, Hung Chin-Sheng, Hsieh Mao-Chih, Chuang Ching-Wen, Ho Yuan-Soon, Chiou Hung-Yi

Abstract excerpt

Previous studies indicated that smoking exposure is associated with an increased risk of breast cancer, and α9-nicotine acetylcholine receptors (α9-nAChRs) are involved in breast tumorigenesis. However, no studies have explored the joint effect of α9-nAChRs (CHRNA9) genes and cigarette smoking exposure on breast cancer risk. A case-control study was conducted on 737 breast cancer patients and 719 age-matched...

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Source

Identifiers

PMID: 25142973
DOI: 10.1093/carcin/bgu179

Genes

CHRNA9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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