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Article

Nicotinic acetylcholine receptors and predisposition to lung cancer.

Current opinion in oncology - 1 Jan 2011

Tournier Jean-Marie, Birembaut Philippe

Abstract excerpt

PURPOSE OF REVIEW: To highlight the current body of knowledge regarding the role of nicotinic acetylcholine receptors (nAChRs) in lung cancer predisposition. RECENT FINDINGS: Smoking is a documented risk factor for cancer, especially for lung carcinomas. Nicotine and its derived carcinogenic nitrosamines contribute to lung cancer development and progression through the binding to nAChRs, which then activate...

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Share to CHRNA3 gene
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Source

Identifiers

PMID: 21045689
DOI: 10.1097/CCO.0b013e3283412ea1

Genes

CHRNA3

Provenance

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