Article
Assessment of high resolution melting analysis as a potential SNP genotyping technique in forensic casework.
Electrophoresis - 1 Nov 2014
Venables Samantha J, Mehta Bhavik, Daniel Runa, Walsh Simon J, van Oorschot Roland A H, McNevin Dennis
Abstract excerpt
High resolution melting (HRM) analysis is a simple, cost effective, closed tube SNP genotyping technique with high throughput potential. The effectiveness of HRM for forensic SNP genotyping was assessed with five commercially available HRM kits evaluated on the ViiA™ 7 Real Time PCR instrument. Four kits performed satisfactorily against forensically relevant criteria. One was further assessed to determine the...
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