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Article

High Resolution Melting (HRM) for High-Throughput Genotyping-Limitations and Caveats in Practical Case Studies.

International journal of molecular sciences - 3 Nov 2017

Słomka Marcin, Sobalska-Kwapis Marta, Wachulec Monika, Bartosz Grzegorz, Strapagiel Dominik

Abstract excerpt

High resolution melting (HRM) is a convenient method for gene scanning as well as genotyping of individual and multiple single nucleotide polymorphisms (SNPs). This rapid, simple, closed-tube, homogenous, and cost-efficient approach has the capacity for high specificity and sensitivity, while allowing easy transition to high-throughput scale. In this paper, we provide examples from our laboratory practice of some...

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Identifiers

PMID: 29099791
DOI: 10.3390/ijms18112316
PMCID: PMC5713285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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