Article
Development of a fast, simple profiling method for sample screening using high resolution melting (HRM) of STRs.
Journal of forensic sciences - 1 Mar 2012
Nicklas Janice A, Noreault-Conti Trisha, Buel Eric
Abstract excerpt
A screening assay has been developed to provide preliminary individualization of crime scene samples thus eliminating expensive, time-consuming short tandem repeat (STR) profiling of nonprobative samples. High resolution melting performed in a real-time PCR instrument is used to detect the slight melting differences between the length and sequence variations of 22 forensic STRs. Three STRs (vWA, D18S51, THO1)...
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