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Article

Influence of donor-recipient CYP3A4/5 genotypes, age and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach.

Pharmacogenomics - 1 Jun 2014

Guy-Viterbo Vanessa, Baudet Henry, Elens Laure, Haufroid Vincent, Lacaille Florence, Girard Muriel, Debray Dominique, Chardot Christophe, Reding Raymond, Wallemacq Pierre, Musuamba Flora

Abstract excerpt

AIM: To characterize the effect of donor and recipient CYP3A4, CYP3A5 and ABCB1 genotypes as well as relevant patient characteristics on tacrolimus pharmacokinetics in pediatric liver transplantation. PATIENTS & METHODS: Data from 114 pediatric liver transplant recipients were retrospectively collected during the first 3 months following transplantation. Population pharmacokinetic analysis was performed using...

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Identifiers

PMID: 25141896
DOI: 10.2217/pgs.14.75

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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