Article
The formin FHOD1 in cardiomyocytes.
Anatomical record (Hoboken, N.J. : 2007) - 1 Sept 2014
Dwyer Joseph, Pluess Marlene, Iskratsch Thomas, Dos Remedios Cristobal G, Ehler Elisabeth
Abstract excerpt
Members of the formin family are known to be involved in the regulation of the actin cytoskeleton. We have recently identified a muscle specific splice variant of the formin FHOD3 and demonstrated its role in the maintenance of the contractile filaments of cardiomyocytes. Here, we characterize the expression and subcellular localization of FHOD3's closest relative, FHOD1, in the heart. Confocal microscopy shows...
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