Article
Cell-cell connection to cardiac disease.
Trends in cardiovascular medicine - 1 Aug 2009
Sheikh Farah, Ross Robert S, Chen Ju
Abstract excerpt
Intercalated disks (ICDs) are highly organized cell-cell adhesion structures, which connect cardiomyocytes to one another. They are composed of three major complexes: desmosomes, fascia adherens, and gap junctions. Desmosomes and fascia adherens junction are necessary for mechanically coupling and reinforcing cardiomyocytes, whereas gap junctions are essential for rapid electrical transmission between cells....
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