Article

Repression of <i>Pdzrn3</i> is required for heart maturation and protects against heart failure

2020-07-30

Abstract excerpt

Heart failure is the final common stage of most cardiopathies. Cardiomyocytes connect with others via their extremities by intercalated disk protein complexes. This planar and directional organization of myocytes is crucial for mechanical coupling and anisotropic conduction of the electric signal in the heart. One of the hallmarks of heart failure is alterations in the contact sites between cardiomyocytes. Yet no...

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Literature Corpus work: a8feae78-57af-5c68-88b6-bb75eca484c9
DOI: 10.1101/2020.07.29.226597

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