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Article

Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.

Experimental cell research - 1 Jul 2006

van der Ven Peter F M, Ehler Elisabeth, Vakeel Padmanabhan, Eulitz Stefan, Schenk Jörg A, Milting Hendrik, Micheel Burkhard, Fürst Dieter O

Abstract excerpt

Filamin c is the predominantly expressed filamin isoform in striated muscles. It is localized in myofibrillar Z-discs, where it binds FATZ and myotilin, and in myotendinous junctions and intercalated discs. Here, we identify Xin, the protein encoded by the human gene 'cardiomyopathy associated 1' (CMYA1) as filamin c binding partner at these specialized structures where the ends of myofibrils are attached to the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16631741
DOI: 10.1016/j.yexcr.2006.03.015

Genes

VASP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.PMID 16631741Read ↗

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The Complete Gene Sequence of Titin, Expression of an Unusual ≈700-kDa Titin Isoform, and Its Interaction With Obscurin Identify a Novel Z-Line to I-Band Linking SystemSemantic proximity Read ↗

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