Article
Transmission disequilibrium test with discordant sib pairs when parents are available.
Human genetics - 1 May 2002
Deng Hong-Wen, Chen Wei-Min, Recker Robert R
Abstract excerpt
The transmission disequilibrium test (TDT) has been employed to map disease susceptibility loci (DSL), while being immune to the problem of population admixture. The customary TDT test (TDT(D)) was developed for affected child(ren) and their parents and was most often applied to case-parent trios. Recently, the TDT has been extended to the situations when (1) parents are not available but affected and nonaffected...
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