The power of independent types of genetic information to detect association in a case-control study design.

Abstract excerpt

There have been many single nucleotide polymorphism-based tests suggested for association analysis in a case-control design. The possible evidence for association comprises three types of information: differences between cases and controls in allele frequencies, in parameters for Hardy Weinberg disequilibrium (HWD) and in parameters for linkage disequilibrium (LD). Here, first we find the pairwise covariances...

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